She keeps diving and escaping before your team can finish her
What to do: Apply Slowing Hex before the mobility chain.
Why it helps: Calico loses most of the movement tools that let her commit and leave safely.

Learn which items answer Calico’s threats, how to play the lane, and when to commit or disengage.
Buy for the threat you are facing. These are situational options, not a build to purchase in full. Tap an item for its breakdown.
Create a punish window by making her spend movement first. Grounding or silencing her matters most when your team can follow up before she escapes. If you are dying to the initial burst, spirit resistance helps you survive long enough to use that window; extra health alone does not address the same problem.
Slowing Hex is the premier answer, Silence Wave or Cursed Relic can create a coordinated focus-fire window, and Spirit Resilience reduces the burst if she still gets her combo off.
Identify what is losing the exchange, then use the answer and timing below.
What to do: Apply Slowing Hex before the mobility chain.
Why it helps: Calico loses most of the movement tools that let her commit and leave safely.
What to do: Build Spirit Resilience or Spellbreaker.
Why it helps: Her dangerous burst is heavily spirit-based, so dedicated spirit defense buys time to survive the combo.
What to do: Use Ethereal Shift during the committed damage window.
Why it helps: Invulnerability lets you wait out the most dangerous part of the sequence instead of trying to outrun it.
What to do: Use Cursed Relic when your team is ready to burst.
Why it helps: The silence and item lock create the short coordinated window Calico normally denies with mobility and defensive cooldowns.
Wait for the movement commitment or coordinate a disable before following. Otherwise the chase can give her another burst-and-escape exchange.
Shoot the cat form when you can do so safely. Keep pressure on her escape rather than letting the transformation end the interaction for free.
Reduces enemy healing and sustain during fights.
Useful answers: Healbane · Toxic Bullets
Limits affected movement skills or creates a grounding/control window for follow-up.
Useful answers: Slowing Hex
Interrupts vulnerable channels or denies an important cast before it starts. Silence alone is not a universal channel interrupt.
Useful answers: Cursed Relic · Silence Wave
Slows the target and disables affected movement abilities.
Use in this matchup:
Silences enemies before an important escape or defensive cast.
Locks enemy actions and strips non-ultimate buffs, but lowers your damage.
Use in this matchup:
Passive resistance against recurring spirit damage.
Use in this matchup:
Adds spirit defense and periodic protection against a large spirit hit.
Brief invulnerability and untargetability to avoid committed damage.
Use in this matchup:
Spirit damage applies anti-heal; affected enemy deaths restore health.
Repeated weapon hits apply anti-heal and maximum-health bleed.